Framycetin skin cream Uses, Side effects, And Storage

Framycetin Cream, also known as Framycetin Sulfate Cream, is a topical medication used to treat skin infections. The active ingredient in framycetin cream uses is framycetin sulfate, which is an antibiotic in the aminoglycoside class. It works by inhibiting the growth and spread of bacteria on the skin, helping to control infections.

Framycetin cream is commonly used to treat minor cuts, burns, abrasions, and infected wounds. It may also be used to prevent infection in surgical incisions and other types of skin injury. The cream is applied directly to the affected area of the skin, usually two to three times a day, or as directed by a healthcare professional.

It is important to note that framycetin cream is only for external use and should not be ingested or applied to open wounds, deep cuts, or mucous membranes. In addition, it is not effective against fungal or viral infections, so it should only be used for bacterial skin infections when prescribed by a doctor.

As with any medication, it is advisable to consult with a healthcare professional, such as a doctor or pharmacist, before using Framycetin cream to ensure its appropriate and safe use for your specific condition. They can give you detailed instructions on how to use the cream and any possible side effects or precautions to be aware of.

How does Framycetin skin cream work?

Framycetin skin cream Uses

Framycetin skin cream, or framycetin sulphate cream, works by using its antibiotic properties to fight bacterial infections on the skin. The active ingredient, framycetin sulphate, is a type of aminoglycoside antibiotic.

When applied topically, Framycetin Cream penetrates the skin and inhibits the growth and spread of bacteria that may be causing an infection. It does this by interfering with bacterial protein synthesis, specifically targeting the bacteria’s ribosomes (the cellular machinery responsible for protein production). By binding to the ribosomes, framycetin disrupts the bacterial protein synthesis process, preventing the bacteria from producing essential proteins for survival and growth. This ultimately leads to the death of the bacteria and helps to control the infection.

Framycetin cream is primarily effective against certain gram-positive and gram-negative bacteria commonly associated with skin infections. However, it is important to note that it may not be effective against all types of bacteria and its use should be based on the diagnosis and recommendation of a healthcare professional.

It is important to follow your doctor’s instructions or the product label when using framycetin cream. The cream is usually applied in a thin layer to the affected area of the skin to ensure good coverage. The frequency and duration of use will depend on the severity and type of infection and will be determined by a healthcare professional.

Framycetin skin cream Uses

Framycetin skin cream uses or framycetin sulfate cream is commonly used for the following purposes

  • Treating minor cuts, scrapes, and abrasions: Framycetin cream can be applied topically to small wounds to prevent or treat bacterial infections. It helps keep the area clean and promotes healing.
  • Treating infected wounds: If a wound becomes infected, framycetin cream may fight the bacterial infection and promote healing. It helps reduce the risk of complications and supports the body’s natural healing mechanisms.
  • Burn care: Framycetin cream is used to treat minor burns, including sunburn. It forms a protective barrier on the affected skin, helping to prevent infection and promote healing.
  • Preventing infection in surgical incisions: After surgery, framycetin cream may be prescribed to prevent bacterial infection of the surgical incision. It is usually used as part of post-operative wound care.

It’s important to note that framycetin cream for skin infections is primarily indicated for bacterial skin infections and should not be used for fungal or viral infections. In addition, its use should be guided by a healthcare professional who can make a proper diagnosis and recommend the appropriate treatment for your specific condition.

Always follow the instructions provided by your healthcare professional or on the product label, including the recommended frequency and duration of use. 

How to use Framycetin skin cream?

When using framycetin skin cream, it is important to follow the instructions given by your healthcare professional or on the product label. Specific instructions may vary depending on the severity and type of infection and your individual condition. However, here are some general guidelines for using framycetin skin cream:

  • Cleanse the afflicted area: Use mild soap and water to gently clean the affected area before applying the lotion.Pat dry with a clean towel.
  • Apply a thin layer: Take a small amount of framycetin cream and apply it in a thin, even layer to cover the affected area. Avoid applying too much cream.
  • Massage gently: Gently massage the cream into the skin until it is absorbed. Wash your hands thoroughly afterward to avoid spreading the cream to unintended areas.
  • Frequency of application: The frequency of application will depend on your doctor’s instructions. In general, framycetin cream for skin infections  is applied two to three times a day. 
  • Duration of treatment: The length of treatment also depends on the specific condition being treated. It is important to complete the full course of treatment even if symptoms improve before the recommended time. Stopping treatment early may result in incomplete eradication of the infection.
  • Follow-up appointments: If you are using Framycetin Skin Cream uses as part of a prescribed treatment plan, keep all scheduled appointments or checkups with your prescriber or health care professional to keep track of your development and alter your therapy as appropriate.

Always consult a healthcare professional for personalized advice on the use of Framycetin Skin Cream uses for your specific condition. They can give you detailed instructions based on your diagnosis and advise you on the appropriate duration and frequency of use.

What are the side effects of Framycetin Cream?

Framycetin skin cream Uses

Like all medicines, Framycetin Cream can cause side effects in some people. Not everyone who uses the cream will experience side effects, and the severity and occurrence of side effects may vary from person to person. Some possible side effects of framycetin skin cream may include

  • Skin irritation: It is possible to experience local skin reactions at the site of application, such as redness, itching, burning, or stinging. If these symptoms persist or worsen, discontinue use and contact your doctor or health care professional.
  • Allergic reactions: Although rare, some people may develop an allergic reaction to framycetin cream. Signs of an allergic reaction may include rash, hives, swelling, difficulty breathing, or tightness in the chest. 
  • Sensitization: Prolonged or excessive use of framycetin cream may cause sensitization, where the skin becomes more sensitive to the cream or other medications. If you experience increased skin irritation or discomfort with prolonged use, discontinue use and consult your doctor.
  • Secondary infections: In some cases, the use of antibiotics such as framycetin cream for skin infections can disrupt the balance of bacteria on the skin, potentially leading to secondary infections. If you experience worsening or new symptoms, such as increased redness, swelling, or drainage from the affected area, see your doctor.
  • Systemic effects: Although rare, systemic effects (effects throughout the body) are possible, especially if the cream is used on large areas of damaged skin or if it is absorbed through open wounds. Systemic effects may include kidney or hearing problems, although these are more commonly associated with systemic administration of aminoglycoside antibiotics than with topical use.

It’s important to tell your doctor if you experience any unexpected or bothersome side effects while using Framycetin Skin Cream. They will be able to assess your specific situation and advise you on the appropriate course of action.

This list may not describe all possible side effects and others may occur. Always read the product label and consult with your doctor or health care professional for complete information regarding possible side effects associated with Framycetin Skin Cream.

Who should not use Framycetin Skin Cream?

Framycetin Cream should not be used by anyone with a known allergy or hypersensitivity to framycetin sulphate or any of the other ingredients in the cream. If you have had an allergic reaction to aminoglycoside antibiotics in the past, it is important to tell your doctor before using framycetin cream.

In addition, certain precautions should be taken and it is recommended to consult with a healthcare professional before using Framycetin Cream if

  • You are pregnant or breastfeeding: The use of Framycetin cream during pregnancy or while breastfeeding should be discussed with a doctor. They will be able to assess the potential risks and benefits and provide appropriate advice.
  • You have extensive or deep wounds: Framycetin cream is usually used to treat superficial skin infections and minor wounds. If you have extensive or deep wounds, it is important to consult a healthcare professional for an appropriate assessment and recommendation.
  • You have a history of kidney problems: Aminoglycoside antibiotics, including framycetin, can potentially affect kidney function. If you have a history of kidney problems or are at increased risk, it is important to discuss the use of framycetin cream with your doctor.
  • You have a history of hearing problems: Although topical use of framycetin cream is not usually associated with hearing problems, if you have a history of hearing problems or are at increased risk, it is advisable to discuss the use of framycetin cream with your doctor or health care professional.

Before starting treatment with Framycetin Cream for skin infections, always give your doctor a full medical history and tell him about all the medicines or treatments you are currently taking. They will be able to assess your particular situation and determine whether Framycetin Cream is suitable for you or whether alternative treatment options should be considered.

Storage and disposal of Framycetin Cream

When storing and disposing of Framycetin Skin Cream it is important to follow the instructions on the product label or given by your doctor. Here are some general recommendations:


  • Store Framycetin Skin Cream at room temperature away from direct sunlight, heat, and moisture.
  • Store in the original packaging or container, tightly closed.
  • Avoid storing in bathrooms or other areas with high humidity.
  • Keep out of the reach of children and pets.


  • Do not dispose of Framycetin Skin Cream with your household waste or flush it down the toilet.
  • Follow local regulations or guidelines for the proper disposal of medicines.
  • If you are unsure about the correct method of disposal, ask a pharmacist or your local waste disposal authority for advice.

It is important to note that the disposal of medicines may vary from region to region. Some locations have specific programs or facilities for the safe disposal of medicines to minimize environmental impact and ensure proper handling. These programs often include designated drop-off locations or collection events for unused or expired medicines. Check with your local pharmacy or healthcare provider for information about disposal options in your area.

If you have any specific questions regarding the storage or disposal of Framycetin cream for skin infections, it is advisable to consult a healthcare professional or pharmacist. They will be able to give you precise instructions based on the specific product and local regulations.

*Disclaimer: Please note that the information provided in this article is for educational purposes only and should not replace professional medical advice. Consult a healthcare professional for personalized guidance and recommendations regarding the Framycetin skin cream uses and Framycetin cream for skin infections.

Author Contribution: Reviewed by Dr. Ram Reddy, MD – General Physician, and Rajeshwar Rao, Pharm D.

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